Ischiospinal Dysostosis in a Child with Pierre-Robin Syndrome

A Case Report: Nager Acrofacial Dysostosis

Introduction: Nager syndrome is a malformation resulting from problems in the development of the first and second branchial arches and limb buds. The cause of the abnormal development of the pharyngeal arches in Nager syndrome is unknown. It is also unclear why affected individuals have bone abnormalities in their arms and legs. Nager syndrome is thought to have an autosomal recessive inherita...

Role of SOX9 in the Etiology of Pierre-Robin Syndrome

Objective(s:Cleft lip/palate are common congenital anomalies, affecting approximately 2/1000 live births. Pierre Robin Sequence is a subgroup of the cleft palate population. Chromosomal abnormalities near the SOX9 gene disrupt the regulation of this gene and prevent the SOX9 protein from properly controlling the development of facial structures, which leads to isolated PRS. The present study wa...

سندرم پیرروبین ( THE PIERRE ROBIN SYNDROME )

The first arch syndrome.

Although disfiguring abnormalities of the face have been a problem to the plastic surgeon for many years and the accompanying embarrassment and morbidity have equally exercised the ingenuity of the psychiatrist, there is yet neither satisfactory treatment nor an adequate mask to shield the sufferer. Accordingly, the search for the cause and possible means of prevention has been intensively purs...

Treacher Collins Syndrome (TCS) and Pierre Robin Sequence — Treatment and Life Expectancy

Treacher Collins syndrome is characterized by the congenital hypoplasia of the zygomatic and mandible bones. It is a syndrome with a concise clinical presentation and mostly surgical treatment. Pierre Robin disorder, on the other hand, is a sequence and not a syndrome, i.e., in Pierre Robin sequence, micrognathia leads to glossoptosis. Glossoptosis, on the other hand, is responsible for the air...